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HEALTH & FITNESS
The Long And Short Of Fatty Acids
A skewed ratio of Omega-3 and Omega-6 fatty acids in your body has its implications, reports Chitra Narayanan
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Are you struggling with those extra inches around your stomach? Finding it difficult to concentrate on work? Well, chances are you are not getting enough exercise, are stressed out and not eating right, but here's one more possible reason to blame for your rising obesity and lack of concentration -- your mom's diet during pregnancy!
A host of new research has now shown that an imbalanced fatty acid composition in the mother's diet during pregnancy and breast feeding can be a reason for the infant's predisposition to obesity. According to cardiologist Dr K. Srinath Reddy, who heads the Public Health Foundation of India, "intra uterine deficiency in Omega-3 could also be responsible for underdevelopment of brain, put you at greater risk of diabetes and cardio vascular disease".
In simple words, this means that your mom probably did not get the right ratio of Omega-6 (Linoleic Acid) and Omega-3 (Alpha-Linoleic Acid) fatty acids during pregnancy. Indians typically are very deficient in Omega-3 and have an overdose of Omega-6. Research has now revealed that excessive amounts of Omega-6 could be implicated in many diseases including cardiovascular disorders, cancer and inflammatory and autoimmune diseases, while increasing Omega-3 levels suppresses this.
By now most of us know the difference between saturated fats, unsaturated fats and polyunsaturated fats. Well, within polyunsaturated fats (PUFA), there are some essential fatty acids (EFAs) like linoleic acid and alpha linoleic acid which cannot be synthesized by our bodies and must be supplied through our diet. Cooking oils are usually the chief source of these EFAs – though you can get them in tiny measure from other sources like nuts, green leafy vegetables, seeds, vegetables, soya and dairy products.
The role of EFAs in our body is probably one of the most researched areas in nutrition today and several studies from Britain, India and the US – many of them still ongoing – show just how important they are to keep our body functioning smoothly. According to nutritionist Ishi Khosla, both Omega-3 and Omega-6 fatty acids form parts of our vital body structures, perform important roles in immune system function and vision. A recent study from Britain (the Durham study) has also shown that adding more Omega-3 to children's diet could improve their concentration, and may even have a role in solving problems like dyslexia.
But the key thing is that these two fatty acids have to be in the right ratio in the body. Urban Indians have one of the most skewed ratios in the world, with their Omega-6 to Omega-3 ratio ranging from 38:1 to 50:1 according to a paper by Artemis P. Simopoulos, President, The Center for Genetics, Nutrition and Health, published in Experimental Biology and Medicine.
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According to World Health Organization (WHO), the recommended ratio of Omega-6 to Omega-3 is 5:1. But many nutrition scientists, after studying the diets of long living healthy populations like the Eskimos and those in the Mediterranean region, prescribe ratios of 2:1.
Part of the reason for this skewed ratio among Indians, according to Khosla, is to do with indiscriminate nutritional recommendations since the 1960s to substitute saturated fat with vegetable oils, high in Omega-6 PUFAs and low in Omega-3 PUFAs. Since then, urban Indians have really got trapped into a vicious cycle of using the wrong oils. The paper by Simopoulous also points out that in earlier generations most children were given a teaspoon of cod liver oil – mainly as a Vitamin A supplementation but it ensured intake of Omega-3 as well. Today that practice is hardly followed.
So Why Is This Ratio So Important?
Those studying the fatty acids have now established that Omega-6 and Omega-3 often seem to be working in competition against each other in the human body. A higher intake of Linoleic Acid (Omega-6) interferes with the process in which the human body converts alpha linoleic acid, which is a short chain fatty acid, into eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) – which are long chain fatty acids and really the ones doing lots of good things in the body. These have anti-inflammatory properties, help reduce the risk of heart disease and also aid nerve growth. DHA, in particular, is needed for normal functioning of retina and brain.
Any imbalance in the ratio is also likely to affect intra cellular communication. As Dr Gaurav Sharma, sports medicine specialist and director, Optima Wellness, points out our cell wall is made up of fats – and if you don't eat the right type of fats, it is going to affect the quality of it. Imagine you are building a wall and substitute cement with some inferior material – the result is going to be a pretty poor quality construction. That's what's happening to our cell walls with disturbance in fatty acid ratios.
Of course there are many doctors who are still pretty conservative about the whole Omega issue. Dr Ravi Kasliwal, interventional cardiologist at the Indraprastha Apollo Hospitals, for instance, says that while Omega-3 undeniably has cardio protective properties, it is highly over-rated and we need to lay more emphasis on cutting out trans fats from our diets.
He is right – but again it links up to the Omega issue, because now research has shown that the more you consume trans fatty acids (these are the really bad fats - those found in chips, some kinds of cheese, hydrogenated oil, commercially baked cookies and so on), it further interferes with the functioning of Omega-6 and Omega-3 in the body.
The Way Forward
If your primary cooking medium is mustard oil or soya oil, your ratios will be all right, says Dr Prema Ramachandran, director, Nutrition Foundation of India, a Delhi-based voluntary agency that works for the upliftment of the nutritional status of Indians. The NFI, incidentally, had done a study on soya oil (rich in Omega-3 fatty acids) supplementation among pregnant women in urban slums, to see if this could be an effective strategy for low income women.
Another study 'Effects of an Indo-Mediterranean Diet on the Omega–6/Omega–3 Ratio in Patients at High Risk of Coronary Artery Disease: The Indian Paradox,' done by Daniel Pella, Gal Dubnov, Ram B. Singh, Rakesh Sharma, Elliot Berry and Orly Manor showed that changing the cooking oils and increasing the fruit and vegetable intake in the diet brought the ratio down to 9.1/1 and a 40 per cent decrease in cardiovascular disease mortality.
While changing oils is definitely part of the solution, as scientists from the Hyderabad based National Institute of Nutrition (NIN) point out, it's not easy for people to implement this at the household level, because you really need awareness about the appropriate combinations, right proportions and so on. Instead, they suggest that edible oil manufacturers should come forth to provide blends of oils in the right fatty acids combinations. NIN scientists – notably former deputy director, Dr Ghafoorunissa, one of India's foremost experts on edible oils and fatty acids -- suggest combining in the 1:1 ratio ground nut, or sesame oil with either canola, mustard or soyabean oil.
Those working in the domain of public health feel that government interventions are necessary in this area. Certain countries have already moved forward and come up with guidelines on Omega-3. Australia, New Zealand and Japan have prescribed a recommended dietary intake level of EPA and DHA at levels between 0.3 and 0.5 grams per day.
Meanwhile, at the household level, Ishi Khosla suggests that increasing consumption of mustard oil, green leafy vegetables, flax seed, mustard, sesame, fenugreek seeds, Urad daal, Rajmah (kidney beans) and soyabean are a good way of raising Omega-3 fatty acid intake. Fish eaters do not really have a problem because they can get these fatty acids from Hilsa, Black pomfret, Katla, Surmai, Salmon, Cod, Halibut, Trout, Herring, Mackerel and Sardines. But still since the issue is the huge amount of Omega-6 we are consuming, which necessitates a proportionately high intake of Omega-3, Gaurav Sharma suggests that a teaspoon of cod liver oil a day or flax seed oil a day to keep the doctor away.
| Riding The Omega Wave |
Even as food scientists and nutrition experts step up research on Omega-3 fatty acid, the commercial impact is already beginning to be felt. The nutraceutical market is currently riding on an Omega wave, thanks to an explosion in demand for the fatty acid. According to a report by Frost and Sullivan, the booming global Omega-3 market is expected to cross $1 billion by 2010. At least a half of this would be accounted by the US market. But the consultancy firm says that sales of Omega-3 fatty acids in Japan, India, Australia, New Zealand, Korea, China and south-east Asian markets will be worth $596.6 million by 2012.
In a separate study, Cygnus India notes that India and China are the fastest growing nutraceuticals markets after the US. In India, the nutraceuticals market which is estimated to be anywhere between Rs 1,100 crore and Rs 1,500 crore is galloping along at an annual growth rate of 40 per cent.
But, Frost & Sullivan also notes that low awareness about the role of Omega-3 and high pricing could be an inhibitor to Omega-3's targeted growth in India. Certainly the Omega-3 supplements available in the market place do not come cheap – Mega 3 retailed by Dr Reddy's Labs is priced around Rs 130 for 30 capsules, while Amway India's Salmon Omega-3 retails for about Rs 1,150 for a bottle containing 60 softgel capsules. Cod liver oil retails for Rs 105 for a 100 ml bottle.
Currently, a major chunk of the global Omega-3 revenues have come from the fish oil market – but with India targeted as an emerging market, vegetarian supplements such as flax seed oil is all set to get a boost.
And one outcome of all the studies on benefits of Omega-3 supplementation in pregnancy and early childhood -- Omega-3 ingredient suppliers like US based Martek Biosciences, which showed an 18 per cent growth in revenues this quarter, are reporting huge demand from infant formula manufacturers! |
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