The NSE Nifty 50 index finished 0.55% lower at 12,031.50 and the S&P BSE Sensex fell 0.39% to 40,979.62.
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Indian shares settled lower for the second straight session on Monday as worries mounted over the economic impact of the new coronavirus outbreak amid a rising death toll.
Global shares traded lower as the virus claimed over 900 lives in China's central Hubei province as of Sunday, a death toll that has exceeded that of the SARS epidemic of two decades ago.
Meanwhile, Beijing lifted some work and travel curbs, offering some reprieve to financial markets.
In the domestic market, metal stocks were the top drags, with the Nifty metals index shedding over 3%.
Zee Entertainment dropped 7.73% and was the top laggard, while UPL Ltd was the top gainer on the Nifty, rising 5.71%.